Semaglutide is a leading GLP-1 receptor agonist medication used to treat type 2 diabetes and promote substantial weight loss. Available as a once-weekly injection (Ozempic for diabetes and cardiovascular risk reduction; Wegovy for chronic weight management) or daily oral tablet (Rybelsus), it works by enhancing insulin release, lowering blood sugar, slowing gastric emptying, and curbing appetite. It also helps reduce the risk of major cardiovascular events in high-risk patients and supports long-term weight maintenance alongside healthy lifestyle changes. Common side effects may include nausea, vomiting, diarrhea, constipation, and abdominal discomfort, which are often mild to moderate and tend to lessen as the body adjusts. Always discuss with a medical professional before starting Semaglutide therapy.